All about Mounjaro: Next Generation of Weight Loss Treatment

The difficulty of dieting does not simply stem from a lack of willpower, but rather from a combination of complex factors such as challenges in blood sugar regulation, hormonal imbalances, and a decrease in basal metabolic rate. This is why, even with strict dietary control and high-intensity exercise, many people find it difficult to lose weight. In fact, obesity is not merely a cosmetic concern but a medical condition that requires treatment, as it is a major risk factor for cardiovascular and metabolic health and is associated with more than 200 complications. Obesity is a major risk factor for cardiovascular and metabolic health and should be regarded not as a mere cosmetic issue, but as a medical condition requiring treatment, as it is associated with more than 200 complications. In this context, a treatment has emerged that addresses multiple factors to support effective weight loss: Mounjaro. Mounjaro has been proven to suppress appetite and promote weight reduction, gaining recognition as a next-generation obesity treatment. In this column, we will take a closer look at Mounjaro in detail.

MOUNJARO’s Active Ingredients & Mechanism

Mounjaro (generic name tirzepatide) is a dual GIP/GLP-1 receptor agonist approved in Korea as a chronic weight management treatment for adult patients with obesity and overweight patients with obesity-related comorbidities. It may also be used as an adjunct to diet and exercise therapy for moderate to severe obstructive sleep apnoea in adult patients with obesity. Its mechanism of action involves simultaneously stimulating the GIP and GLP-1 receptors, which are incretin hormones, thereby inducing potent appetite suppression, reduced food intake, delayed gastric emptying, and improved blood glucose control. Furthermore, it demonstrates a mechanism optimised for weight loss by enhancing the body's energy metabolism efficiency and promoting fat burning. It is attracting attention as a new class of diet treatment that goes beyond mere blood glucose stabilisation, driving fat-focused reduction and improving body composition.

A New Paradigm in Obesity Treatment: Mounjaro’s Weight Reduction Results

In the landmark obesity clinical trial SURMOUNT-1, patients receiving 15 mg of Mounjaro achieved an average 22.5% weight reduction, while even the minimum maintenance dose of 5 mg resulted in a significant 16.0% reduction. Notably, the body fat reduction rate (33.9%) was nearly three times higher than the lean mass reduction rate (10.9%), demonstrating that Mounjaro not only reduces overall body weight but also improves body composition with a focus on fat reduction.

Furthermore, in the SURMOUNT-5 study comparing Mounjaro with the GLP-1 monotherapy Semaglutide, Mounjaro achieved an average 21.6% weight loss, clearly outperforming Semaglutide at 15.4%. Waist circumference was also reduced by more than 20 cm on average in the Mounjaro group, confirming its superior effect in abdominal fat management.

In this way, Mounjaro enables a healthier and more balanced weight loss by delivering powerful overall reduction and targeted fat-focused improvement.

AB Clinic’s Personalized Weight Loss Program with Mounjaro For a more effective diet experience

AB Clinic combines Mounjaro with its own signature products – AB Fat Dissolving Injection and AB Slim Infusion – as well as high frequency devices to provide a tailored weight-loss program that maximizes results.

AB Fat Dissolving Injection

AB’s exclusive fat-dissolving injection (containing ingredients such as PPC, hyaluronic acid, and plant extracts) helps safely break down localized fat without concerns about side effects. It also promotes cellulite reduction and waste elimination.

AB Slim Infusion

This signature diet infusion activates metabolism, promotes fat burning, and supports rapid weight reduction. Enriched with antioxidant and detoxifying components, it enhances skin health while delivering a more effective weight loss experience.

AB High-Frequency Device

The high-frequency device stimulates tissue activation, removes waste, and breaks down fat through thermal energy while promoting collagen and elastin regeneration. This improves skin elasticity, enhances overall body balance, and completes body contouring by restoring firmness to areas that have lost tone after dieting.

In this way, AB Clinic combines Mounjaro with its signature programs to deliver greater weight loss results while helping you achieve a healthier, more sculpted body.

The Importance of Healthy Weight Loss Without Rebound

The goal of weight loss is not simply short-term reduction on the scale, but maintaining a healthy weight in the long term without rebound. Since obesity is a condition that requires comprehensive management—including lifestyle modification, medication, and psychological support—a personalized approach is essential. At AB Clinic, our dedicated team of dermatologists provides a systematic and safe individualized program. With Mounjaro, we offer a sustainable weight loss solution designed to help patients regain both a healthy body weight and their confidence.