Rejuran HB: Why It’s Recommended for Those Sensitive to Pain

Rejuran has earned a strong position in the skin booster field due to its ability to address a wide range of age-related concerns such as fine lines, weakened elasticity, declining regenerative capacity, and compromised skin barrier function. However, Rejuran Healer developed a reputation for being painful, largely because of its high viscosity and the injection resistance associated with its formulation. This caused many pain-sensitive patients to hesitate before undergoing treatment.

To solve this issue, Rejuran HB was specifically developed with lidocaine and improved viscosity to significantly reduce discomfort while preserving Rejuran’s hallmark regenerative effects. This optimized formula makes Rejuran HB the preferred option for individuals who want skin regeneration benefits without excessive injection pain.

In this column, we examine why Rejuran HB is considered the better choice for those sensitive to pain.

Why Rejuran Healer Causes Pain

Rejuran Healer’s original formulation often results in more discomfort for several reasons:

· High viscosity increases needle insertion pressure

· High viscosity creates greater injection resistance, leading to pain

· Deep dermal injection depth maximizes needle irritation

These structural characteristics explain why the Healer formulation tends to feel sharper and more painful during treatment.

Why Rejuran HB Causes Less Discomfort

Rejuran HB offers a more comfortable treatment experience due to several improvements in its formula:

• Lower viscosity reduces injection pressure and pain

• The hyaluronic acid (HA) blend allows smoother injection flow with less resistance

• Lidocaine provides immediate and effective pain relief

• Higher molecular weight HA may contribute to longer-lasting embossing, but with less discomfort compared to Rejuran Healer

Because of these factors, Rejuran HB is the most recommended formulation for patients concerned about Rejuran-related pain.

Key discomfort-reducing features:

• Reduced insertion pressure

• Smoother injection feel

• Stronger comfort during and after treatment

Comparing Rejuran Products

Rejuran products offer different formulations tailored to varying skin types, needs, and pain sensitivity levels.

Rejuran Healer

• Original PN-based regenerative formula

• Excellent for fine lines, pores, and elasticity

• Promotes collagen synthesis

• Higher viscosity leads to more discomfort

Rejuran HB

• PN + HA + lidocaine

• Regeneration + hydration + pain relief at once

• Smooth viscosity = significantly less pain

• Strong hydration delivery

• Most comfortable Rejuran treatment

Rejuran I

• Designed for the thin, delicate eye area

• Improves fine lines and elasticity

• Very smooth viscosity = minimal swelling and discomfort

Rejuran S

• High-concentration PN for scars

• Strong tissue-filling effect

• Heaviest viscosity = most discomfort

Recommended Treatment Schedule for Rejuran HB

Here is the standard Rejuran HB treatment protocol:

Standard Protocol

• Typically 3–4 sessions spaced 3–4 weeks apart

• Aligned with the skin’s natural 28-day regeneration cycle

Maintenance Therapy

• One session every 3–6 months

• For barrier-weakened or chronically dry skin, a 3-month interval is recommended

This schedule supports consistent collagen regeneration and maintains hydration benefits.

Why the “Embossing” from Rejuran HB May Last Longer

Because of the formulation and structural design of Rejuran HB, the embossing effect—small bumps or swelling at injection sites—can remain longer than with standard Rejuran treatments. This is not an adverse reaction; instead, it reflects how long the PN + HA components remain active within the tissue.

Main Reasons for Prolonged Swelling

1. Slow PN absorption rate

2. Stabilizing effect of high-molecular-weight HA

3. Longer residence time of the PN + HA combined formula

Why Some Patients Experience Prolonged Discomfort

• Mild inflammation triggered by PN’s regenerative activity

• Individual sensitivity to HA

• Persistent tactile sensation from the longer-lasting formula

Overall, the extended duration indicates continued regenerative action, not a complication.

Achieving Safe and Effective Rejuran Results

Rejuran HB enhances regeneration and hydration through its PN + HA composition, but its clinical results can vary significantly depending on the injector’s skill, understanding of viscosity, and injection depth control. Proper pressure, depth, and fractional injection technique are essential to avoid unevenness, nodules, or irregular distribution.

At AB Beauty&Cell Clinic Gangnam, specialized dermatology physicians analyze each patient’s skin thickness, elasticity, hydration, and sensitivity to determine the safest and most effective injection depth and dosage.

Our protocol includes:

• Advanced layering techniques

• Controlled injection pressure

• Customized injection speed per facial region

These methods minimize discomfort and optimize regeneration, ensuring safe and consistent results even for highly sensitive patients.